created by essedicom
 Home
Welcome
  
 Pioneers in Microdermabrasion
Technology Description
Ultrapeel Crystal
Ultrapeel II
Before & After Pictures
Treatment Video
  
 Innovators in Needles free injections systems
Dermoelectroporation Technology
Ultrapeel Transderm Ionto System
Testimonials
Frequently Asked Questions
FDA Clearance and Patents
Educationals for Doctors
Before and After Pictures
Compounding Pharmacies
Transderm Ionto Meso System
Treatment Video
TRANSDERM IONTO DEP - NEW!
  
 Newsroom
In the News
Press Kit
Media Inquiries
  
 Customer Service and Support
Training
Equipment Support
Supply Order Form
  
 New Generation of IPL Mattioli Pulse Q-FRACTIONAL Technology- Now FDA cleared
Pulse II
Pulse III
Video Skin Rejuvination
Video Brown Spot Removal
Video Epilation Underarm
Video Body Epilation
  
 Microdermabrasion
Technology Description
Ultrapeel Pepita
Aesthipeel
  
 Customer Service & Support
Training
Equipment Support
Mattioli eBay Store
  
 Facial rejuvenation
Microdermabrasion
Still Scared of Injections?
  
 Body Shaping
Still scared of injections?
  


DEP 
 


DEP (DermoElectroPoration) System is the new Non Invasive, Stand alone powered drug-delivery system carrying DermoelectroporationÒ  Technology to deliver Ionic drug solution into the body for medical purposes.

As result of more than five years researches, Mattioli Dermoelectroporation®,

technology is consolidated to be an incredible procedure that allows the transdermal delivery of whatever substance operators  want ,  which are otherwise not absorbed into the skin because of the typology and dimension of their own molecules.

Dermoelectroporation® infact, increases the skin's permeability just using some skin's water based channels  opened by a particular controlled current delivered to the patient and allowing the substances to absobed till hypodermis and muscle membranes.

The system  has been FDA approved for the "local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections".

DEP System is made of the following devices:

§   Power supply and control base.

§   DEP Transdermal delivery handpiece with

§   Super Precision Liquid Dispenser – Super PLD.

Macromolecules (such as Hyaluronic Acid) previously not transdermally deliverable by traditional Ionthophoresis are now successfully deliverable due to the new DermoelectroporationÒ Technology.


DEP System features:

     Homogeneous drug delivered on the selected area.

     Real time control on the amount of drug to delivered.

     Real time patient's skin impedance measurement for successful drug      delivery.

     Drug administration in a timely manner to  avoid waste of product with 100% protection against external agents.

     No Electrolysis effect – No drug PH modification

     No need of Pre-charged compounds/ Carrying Gels/ specific products or particular preparations.


DEP System  ensures speed of action, easier regulation of either current delivery and vibration and monitors skin impedance on real time to give users the final results they expect. The new revolutionalry handpiece allows users to see and manage at best the delivery with no waste of product and getting optimal results.

Operators will enjoy the accuracy provided by the DEP System Handpiece for any skin condition and for any length of treatment.

Patients will enjoy treatments with DEP System due to the very high comfortable sessions. Vibration feature  makes electrical pulses delivery perception to decrease significantly and the handpice won't allow undesired spilling of product.

 
 
Features 
 

Easy to use.

FDA cleared as alternative to injections.

New Internationally Patented proprietary Dermoelectroporation®  Technology.

Non invasive.

Current delivery perception protected.

Control on homogeneous drug delivery.

100% drug protection against external agents.

Real time skin impedance measurement feature.

Real time transdermal delivery monitoring.

Control on either amount of drug
to be delivered and time of treatment.

Capability of Transdermal Delivery of ionic drug solution of macromolecules (greater than 800.000Dalton!!).

 

Users don't need to change their sexisting protocols.



Some applications:

Hyperhidrosys
• Skin Rejuvenation treatments
• Wrinkles treatments
• Pre laser treatments
• Pre and post plastic surgery sessions
• Skin Whitening treatments
• Steroids applications
• Aesthetic applications
• Replacing injections

Mesotherapy applications

and many others...


Some deliverable drugs:

• Type A Botulinum Toxine
• Phosphatidylcoline
• Hyaluronic Acid
• Aminophylline
• Grow Factors
• Amino Acids
• L-Carnitine
• Lidocaine
• Heparine
• Collagen
• Vitamins
• Steroids
• Elastine
and many others...

 


Benefit to patients:

 

Astonishing results

Comfortable  treatment sessions

No irritations, burnings or inflammations for return electrode placement

No trauma from injections

 
 
Dermoelectroporation 
 

Dermoelectroporation® is a new named and patented proprietary  technology of Mattioli Engineering Labs of Florence, Italy. As result of more than five years researches, Mattioli Dermoelectroporation®,

technology is consolidated to be an incredible procedure that allows the transdermal delivery of whatever substance operators  want ,  which are otherwise not absorbed into the skin because of the typology and dimension of their own molecules. Dermoelectroporation®  infact, increases the skin's permeability just using some skin's water based channels  opened by a particular controlled current delivered to the patient and allowing the substances to absobed till hypodermis and muscle membranes.


Dermoelectroporation® allows ionic dug solutions to penetrate down till Hypodermis and it is faster than traditional Ionthophoresis.

With Dermoelectroporation® micro and macro-molecules (greater than 800 Kdalton in 
size, such as Hyaluronic, Vitamins, Amino acids, Heparin, Antinflammatories etc) are safely delivered into the body without either modification of the  ionic drug solutions pH and Electrolysis effect of the ionic solution itself. 
This was not possible with traditional Ionthophoresis systems before.

 
 
 
MATTIOLI ENGINEERING CORPORATION- @contact