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COMBINED DERMOELECTROPORATION® plus MICRODERMABRSION® DEVICES 
 

Ultrapeel® II Plus Transderm® Meso® System  

Ultrapeel® II Transderm® Meso® System® is the newest needles free injection system for transdermal drug delivery endorsing Dermoelectroporation® technology and it is cleared by the US FDA as alternative to injections.

As result of our last five years researches, Mattioli Engineering has recently introduced into the market the new Ultrapeel® II Transderm® Meso® System® an incredible procedure that allows the transdermal delivery of whatever substance the doctor wants,  which are otherwise not absorbed into the skin because  of the typology and dimension of their own molecules.

Ultrapeel® II Transderm® Meso® System® makes the skin tissues permeable to macromolecules (up to million daltons – Biopsy available), in a non invasive way. That's why the American FDA cleared the system as "Can be used as alternative to injections".

Ultrapeel® II Transderm® Meso® System® has been designed to make doctors obtain all the benefits from drugs transdermal delivery procedures  avoiding limits and side effects traditional techniques usually give. Ensures speed of action, easier regulation of either current delivery and vibration and monitors skin impedance in real time to give users the final results they expect.

Ultrapeel® II Transderm® Meso® System® can be used for skin bio-revitalization treatments, cellulite treatments, pre-laser applications,  pre and post skin resurfacing surgery procedures. It can be used also as alternative to injections for all Mesotherapy applications using a lower amount of product to deliver  with no traumas, injuries and irritations for patients. Also, physical rehabilitation treatments and  sports medicine treatments are included.

 

Ultrapeel® II Transderm® Meso® System® is composed by:

 Ultrapeel® II microdermabrader allowing the proper skin prep.

 Transderm® Meso® delivery display allowing users to adjust the current to be delivered and select the proper vibration level along with a real time patient's skin impedance meter for homogeneous drug delivery.

 9 electrodes patient applicator for big areas applications.

 3 electrodes patient applicator for small areas applications.

 Super Precision Liquid Dispenser (Super PLD) to timely deliver the right amount of drug.

 

Ultrapeel® II Transderm® Meso® System® transdermally delivers whatever substance the user wants into the skin , using some particular electrical pulses applied right after a preliminary microdermabrasion. All Transderm® Meso® System® are equipped by Super Precision Liquid Dispenser - Super PLD  fully digitally controlled device allowing users to:

 Administer the drug in a timely manner

 Control the amount of product  to deliver

 Avoid users to  waste the products during the sessions.

 100% protection against external agents intrusion (water, fluid, corundum etc..).



Pdf Datasheet

 

 

 

Ultrapeel® II Plus Transderm® Digital

 

Ultrapeel® Transderm® Digital is an intellingent powered drug-delivery system carrying Transderm® that has been FDA cleared for the "local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections".

Ultrapeel® Transderm® Digital uses Dermoelectroporation® technology to deliver any active ingredient into the body and it monitors in Real time the patient's skin characteristics, to

modify the pulse delivery accordingly, to ensure 100% delivery success and maximum flexibility.

Ultrapeel® Transderm® Digital consists of :

 Ultrapeel® II plus digitally controlled microdermabrader

 Transderm® Digital with applicator (user selectable)

 Super precision liquid dispenser - SPLD Macromolecules (> 15,000dalton) not transdermally deliverable by traditional ionthophoresis are now successfully and safely deliverable by this outstanding Dermoelectroporation® technology (up to 2,000,000dalton and more).

 

Patients will enjoy treatments with Ultrapeel® Transderm® Digital due to the very high comfortable sessions. Vibration features make electrical pulses delivery perception to decrease significantly.

Ultrapeel® Transderm® Digital ensures speed of action, easier regulation of all treatment parameters in real time to give users the final results they expect in a safe and reliable way.

The ergonomic and lightweight applicators allow users to work greatly for patient.

 

Some of the Benefit to patients:

 Astonishing results from the 1st session

 "Taylored on patient" protocols

 Comfortable treatments

 No downtime or social life restriction of any sort

 No irritations, burnings or inflammations

 No trauma from injections

 Faster outcomes

Pdf Datasheet

 




 
 
PURE DERMOELECTROPORATION PRODUCTS 
 

DEP System

DEP(DermoElectroPoration®) System is the new non invasive, stand alone powered drug-delivery system carrying Dermoelectroporation® Technology to deliver Ionic drug solution into the body for medical purposes. As result of more than five years researches, Mattioli Dermoelectroporation®, technology is consolidated to be an incredible procedure that allows the transdermal delivery of whatever substance operators want , which are otherwise not absorbed into the skin because of the typology and dimension of their own molecules.

Dermoelectroporation® infact, increases the skin's permeability just using some skin's water based channels opened by a particular controlled current delivered to the patient and allowing the substances to absobed till hypodermis and muscle membranes.

The system has been FDA approved for the "local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections".

DEP System is made of the following devices:

 Power supply and control base.

 DEP Transdermal delivery handpiece with

 Super Precision Liquid Dispenser – Super PLD.

Macromolecules (such as Hyaluronic Acid) previously not transdermally deliverable by traditional Ionthophoresis are now successfully deliverable due to the new DermoelectroporationÒ Technology.

 DEP System features:

 Homogeneous drug delivered on the selected area.

 Real time control on the amount of drug to be delivered.

 Real time patient's skin impedance measurement for successful drug delivery.

 Drug administration in a timely manner to avoid waste of product with 100% protection

against external agents.

 No Electrolysis effect – No drug PH modification.

 No need of Pre-charged compounds/carrying Gels/ specific products or particular preparations.

DEP System ensures speed of action, easier regulation of either current delivery and vibration and monitors skin impedance on real time to give users the final results they expect. The new revolutionalry handpiece allows users to see and manage at best the delivery with no waste of product and getting optimal results. Operators will enjoy the accuracy provided by the DEP System hand-piece for any skin condition and for any length of treatment. Patients will enjoy treatments with DEP System due to the very high comfortable sessions. Vibration feature makes electrical pulses delivery perception to decrease significantly and the handpiece won't allow undesired spilling of product.


Transderm Digital Stand Alone 

 

 

Transderm® Digital is the new born non invasive, stand alone powered drug-delivery system carrying Dermoelectroporation® Technology to deliver ionic drug solution into the body for medical purposes.

As result of more than five years researches, Mattioli Dermoelectroporation®, technology is consolidated to be an incredible procedure that allows the transdermal delivery of whatever substance operators want, which are otherwise not absorbed into the skin because of the typology and dimension of their own molecules. Dermoelectroporation® in fact, increases the skin's permeability just using some skin's water based channels opened by a particular controlled current delivered to the patient and allowing the substances to absorbed till hypodermis and muscle membranes.


The system has been FDA approved for the "local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections".

 

Transderm® Digital is made of the following devices:

 Transderm® Digital with two applicators

 Transderm® needle Free Syringe

 

Pdf Datasheet

 

 
 
 
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